mosaik

Genetics

Software Description

MOSAIK is a reference-guided assembler comprising of two main modular programs:

  • MosaikBuild
  • MosaikAligner

MosaikBuild converts various sequence formats into Mosaik's native read format. MosaikAligner pairwise aligns each read to a specified series of reference sequences and produces BAMs as outputs. At this time, the workflow consists of supplying sequences in FASTA, FASTQ, Illumina Bustard & Gerald, or SRF file formats and producing results in the BAM format.

Unlike many current read aligners, MOSAIK produces gapped alignments using the Smith-Waterman algorithm. MOSAIK is written in highly portable C++ and currently targetted for the following platforms: Microsoft Windows, Apple Mac OS X, FreeBSD, and Linux operating systems. Other platforms can easily be supported upon request.

MOSAIK is multithreaded. If you have a machine with 8 processors, you can use all 8 processors to align reads faster while using the same memory footprint as when using one processor.

MOSAIK supports multiple sequencing technologies. In addition to legacy technologies such as Sanger capillary sequencing, our program supports next generation technologies such as Roche 454, Illumina, AB SOLiD, and experimental support for the Helicos Heliscope.


Info

Module Name

mosaik

Last Updated On

08/29/2023

Support Level

Secondary Support

Software Access Level

Open Access

Home Page

http://code.google.com/p/mosaik-aligner/

Documentation

Software Description

MOSAIK is a reference-guided assembler comprising of two main modular programs:

  • MosaikBuild
  • MosaikAligner

MosaikBuild converts various sequence formats into Mosaik's native read format. MosaikAligner pairwise aligns each read to a specified series of reference sequences and produces BAMs as outputs. At this time, the workflow consists of supplying sequences in FASTA, FASTQ, Illumina Bustard & Gerald, or SRF file formats and producing results in the BAM format.

Unlike many current read aligners, MOSAIK produces gapped alignments using the Smith-Waterman algorithm. MOSAIK is written in highly portable C++ and currently targetted for the following platforms: Microsoft Windows, Apple Mac OS X, FreeBSD, and Linux operating systems. Other platforms can easily be supported upon request.

MOSAIK is multithreaded. If you have a machine with 8 processors, you can use all 8 processors to align reads faster while using the same memory footprint as when using one processor.

MOSAIK supports multiple sequencing technologies. In addition to legacy technologies such as Sanger capillary sequencing, our program supports next generation technologies such as Roche 454, Illumina, AB SOLiD, and experimental support for the Helicos Heliscope.

General Linux

To load this module for use in a Linux environment, you can run the command:

module load mosaik

Depending on where you are working, there may be more than one version of mosaik available. To see which modules are available for loading you can run:

module avail mosaik

Agate Modules

Default

2.2.3

Other Modules

2.1.33, 2.2.3

Mangi Modules

Default

2.2.3

Other Modules

2.1.33, 2.2.3

Mesabi Modules

Default

2.2.3

Other Modules

2.1.33, 2.2.3