Minnesota Supercomputing Institute
With regards to the safety measures put in place by the university to mitigate the risks of the COVID-19 virus, at this time all MSI systems will remain operational and can be accessed remotely as usual. The only planned outages concern our in-person Helpdesk and tutorials. More information, as well as alternative remote support options, can be found at MSI COVID-19 Continuity Plan
Wednesday, December 7, 2016
MUSCLE, MUltiple Sequence Comparison by Log-Expectation, is a program for creating multiple alignments of amino acid or nucleotide sequences. MUSCLE is claimed to achieve both better average accuracy and better speed than ClustalW2 or T-Coffee, depending on the chosen options.
To run this software interactively in a Linux environment run the commands:
module load muscle
muscle -in <seqs.fa> -out <alignedseqs.fa>
For documentation, refer to MUSCLE Homepage.