From the SOLVE/RESOLVE home page:
SOLVE/RESOLVE is a program that can carry out all the steps of macromolecular structure determination from scaling data to calculation of an electron density map, automatically.
SOLVE does everything crystallographers do to solve an MIR or MAD structure, but automatically. It scales data, solves Patterson functions, calculates difference Fouriers, looks at a native Fourier to see if there are distinct solvent and protein regions, and can score partial MAD and MIR solutions to build up a complete solution. SOLVE has solved MIR and MAD structures with up to 52 heavy-atom sites.