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Tutorial Details: Introduction to Coot

Date: Tuesday, October 28, 2008, 01:30 pm - 03:30 pm
Location: 575 Walter
Instructor(s): Can Erol Ergenekan, MSI

The Crystallographic Object-Oriented Toolkit (Coot) is a free, academic software package mainly used by crystallographers to build, manipulate, refine and validate protein structures. Coot is similar to programs like O and Insight II in functionality, with the advantage of having many of the building and validation features automated. Coot also has the added benefit of being able to read the main binary files of CCP4 (.mtz files) directly to allow for easy map creation and refinement of the structure.

This hands-on tutorial will bring the user up to speed on using Coot for the modeling portion of protein crystal structure refinement.

Prerequisites: Knowledge of molecular modeling and crystallography is helpful