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Tutorial Details: Next-Generation Sequencing Genotyping

Date: Thursday, August 12, 2010, 01:00 pm - 03:00 pm
Location: 575 Walter
Instructor(s): Wayne Xu, MSI

Genotyping refers to the process of determining the genotype of an individual by sequence information. Different genotypes may be associated with specific phenotypes; therefore, genotyping can be used for genetic-associated disease studies, drug-resistance association studies, high-yield genes mapping or plant lines selection, etc.

There are many different methods for genotyping. Recent technological advances in high-performance genotyping methods include array or bead-based genotyping and next-generation sequencing genotyping.

This tutorial will discuss Illumina Solexa sequencing for genotyping, including the Solexa technique design and the sequencing workflow. We will also demonstrate the GenomeStudio and SOAP software for Solexa sequencing genotyping.

Level: Introductory
Prerequisites: None