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Tutorial Details: Introduction to Protein Structure Motif Analysis using Promotif

Date: Thursday, April 21, 2005, 01:00 pm - 03:00 pm
Location: Room 138 Cargill
Instructor(s): Wayne Xu, MSI, Assistant Professor Yuk Y Sham PhD, Center for Drug Design

There are many proteins that have similar functional and structural features but share a very low sequence similarity. For these proteins, it is not possible to apply homology modeling to predict their protein structures.

Instead, one may examine the structure motifs. Structure motifs are individual structural features including secondary structure, sulfide bridges, turns, etc. They are essential in how a protein folds and assembles into the overall tertiary structure. In this tutorial, we will give an overview of the various types of protein structure motifs and demonstrate one of the software packages for performing structure motifs analysis, called Promotif.

Prerequisites: Biology