You are here
Ying Zhang, Ph.D.
As a brief summary of my education and previous experience, I graduated from the University of Science and Technology of China (2002) and pursued a PhD degree at Penn State University (2009). I started my research in Bioinformatics since the very beginning of my PhD period and have been working on several great projects, focusing on computational modeling of the GATA-1-related Erythroid regulation. After that, I joined Dr. Eric Harvill’s lab to apply comparative genomics on the understanding of the pathogenesis of B. pertussis, the causative agent of whooping cough.
My expertise could be pinpointed into the following categories:
1. Good understanding on complex model systems: Hematopoieses system (human and mouse cell line) and human pathogen (bacteria – Bordetellae)
2. Proficient in Comparative Genomics analysis: Genome manipulation, including assembly, annotation and alignment; Sequence level analysis, including binding site motif discovery, quantifying conservation, repeats identification; Training models using real-world data
3. Proficient in Next-Generation Sequencing technologies: short reads mapping, assembling and peak calling
4. Programming Skills: Python, R (statistical) and C, excellence in Galaxy platform
Besides the above dry lab expertise, I am also familiar with some of the traditional wet lab technologies, such as PCR, transient transfection and stable transfection assays, linkage mapping, positional cloning and sequencing.